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  • Bioethics Forum Essay

    DarkCo Petroceuticals, Angelic Solar Panels, and the SUPPORT Study

    As the author of the article that claimed “vindication” for the SUPPORT study, I would like to respond to Professor Latham’s insightful interpretation of the issues in the case. Like Professor Latham, I will...

    Read “DarkCo Petroceuticals, Angelic Solar Panels, and the SUPPORT Study”

  • Bioethics Forum Essay

    The SUPPORT Study Case: Not Vindication

    Last week’s New England Journal of Medicine featured, and had an editorial about, a short opinion piece by John Lantos about the recent decision in Looney v. Moore. In that case, a Federal District judge dismissed the...

    Read “The SUPPORT Study Case: Not Vindication”

  • Bioethics Forum Essay

    Ethics, Optics, and Medicine as Work: Backstage at Planned Parenthood

    Two days after a hidden camera video of Planned Parenthood’s senior director of medical services was released, the president of Planned Parenthood Federation of America, Cecile Richards, apologized for Dr....

    Read “Ethics, Optics, and Medicine as Work: Backstage at Planned Parenthood”

  • Bioethics Forum Essay

    Suing for Justice? More on the U.S. STD Studies in Guatemala

    On April 1, a $1 billion lawsuit was filed by three law firms based in the United States and Venezuela against Johns Hopkins University, the Rockefeller Foundation, and Bristol-Myers Squibb on...

    Read “Suing for Justice? More on the U.S. STD Studies in Guatemala”

  • Bioethics Forum Essay

    OHRP’s Dangerous Draft Guidance

    In October, the federal Office for Human Research Protections issued a “Draft Guidance on Disclosing Reasonably Foreseeable Risks in Research Evaluating Standards of Care.” It follows the controversy that erupted in 2013...

    Read “OHRP’s Dangerous Draft Guidance”

  • Bioethics Forum Essay

    Trapper’s Care in the Animal ER and Frank Talk about Costs

    “The capacity for suffering and enjoying things is a prerequisite for having interests at all, a condition that must be satisfied before we can speak of interests in any meaningful...

    Read “Trapper’s Care in the Animal ER and Frank Talk about Costs”

  • Bioethics Forum Essay

    Facebook’s Emotion Experiment: Implications for Research Ethics

    Several aspects of a recently published experiment conducted by Facebook have received wide media attention, but the study also raises issues of significance for the ethical review of research more generally. In...

    Read “Facebook’s Emotion Experiment: Implications for Research Ethics”

  • Bioethics Forum Essay

    Chronicling the Tuskegee Syphilis Study Through Art

    I was born in the John A. Andrew Memorial Hospital in 1974 where the Tuskegee Syphilis Study took place. I have had a lifelong curiosity about the ethics of the study and...

    Read “Chronicling the Tuskegee Syphilis Study Through Art”

  • Bioethics Forum Essay

    A Medical Student’s Call for Action Against Research Misconduct

    Is research misconduct and abuse the norm in the University of Minnesota’s Department of Psychiatry? A recent investigative report from KMSP News in the Twin Cities suggests that the answer may well...

    Read “A Medical Student’s Call for Action Against Research Misconduct”

  • Bioethics Forum Essay

    Orphans to History: A Response to the Bucharest Early Intervention Project Investigators

    I appreciate the thoughtful responses to my essay on the ethics of the Bucharest Early Intervention Project (BEIP), from its investigators, Drs. Fox, Zeanah and Nelson and from Dr. Millum, one of the bioethicists...

    Read “Orphans to History: A Response to the Bucharest Early Intervention Project Investigators”

  • Bioethics Forum Essay

    New Recommendations for Research with Human Subjects Who Lack Consent Capacity

    The New York State Task Force on Life and the Law released its Report and Recommendations for Research with Human Subjects Who Lack Consent Capacity today, which analyzes the ethical and legal implications...

    Read “New Recommendations for Research with Human Subjects Who Lack Consent Capacity”

  • Bioethics Forum Essay

    Canada Confronts its Own “Tuskegee” Studies

    Last summer’s revelations that malnourished Aboriginals in Canada served as unwitting and unprotected subjects in nutritional experiments in the 1940s and 1950s brought a sharp reaction–though the research took place...

    Read “Canada Confronts its Own “Tuskegee” Studies”

  • Bioethics Forum Essay

    Romanian Orphans Study: A Bioethicist Responds to Ethical Concerns

    Last month, Joseph J. Fins published a commentary on this blog criticizing the ethics of the Bucharest Early Intervention Project (BEIP)–a randomized, controlled trial of Romanian children who had been in orphanages,...

    Read “Romanian Orphans Study: A Bioethicist Responds to Ethical Concerns”

  • Bioethics Forum Essay

    Romanian Orphans Study: Investigators Respond to Ethical Questions

    We appreciate having an opportunity to respond to the commentary on the Bucharest Early Intervention Project (BEIP) by Joseph Fins. We respect his status as a leading bioethics authority, although we are...

    Read “Romanian Orphans Study: Investigators Respond to Ethical Questions”

  • Bioethics Forum Essay

    The Push for Data Transparency and Implications for Research

    Some of the most hotly debated questions making the rounds these days include who should interpret, distribute, review, and receive data, and with good reason. From WikiLeaks to National Security...

    Read “The Push for Data Transparency and Implications for Research”

  • Bioethics Forum Essay

    Getting By with a Little Help from Your Friends

    If the mutilated body of one of your research subjects is discovered in a blood-soaked bathroom, who should investigate the death?  If you want to be cleared of blame, it’s...

    Read “Getting By with a Little Help from Your Friends”

  • Bioethics Forum Essay

    Romanian Orphans: A Reconsideration of the Ethics of the Bucharest Early Intervention Project

    Recently I had a Susan Reverby moment. Reverby is the Wellesley historian best known for unearthing the revelations of the Guatemalan syphilis and gonorrhea studies conducted by the United States Public Health...

    Read “Romanian Orphans: A Reconsideration of the Ethics of the Bucharest Early Intervention Project”

  • Bioethics Forum Essay

    Support for Returning Results of Alzheimer’s Disease Biomarker Research

    This used to be a purely academic question: If you could know, years before you had symptoms of Alzheimer’s disease, that you were likely to develop it–and there was no...

    Read “Support for Returning Results of Alzheimer’s Disease Biomarker Research”

  • Bioethics Forum Essay

    Dozens of Bioethicists Air Views on SUPPORT Study Controversy

    For those following the SUPPORT Study controversy, the New England Journal of Medicine published this week a letter to the editor organized by Ruth Macklin, Alice Dreger, and me, and signed by 45 “physicians,...

    Read “Dozens of Bioethicists Air Views on SUPPORT Study Controversy”

  • Bioethics Forum Essay

    SUPPORT Update: OHRP’s Compliance Actions on Hold

    In a thoughtful, nuanced letter to the University of Alabama (the home of the Principal Investigator of the SUPPORT study), the Office for Human Research Protection announced that it has “put...

    Read “SUPPORT Update: OHRP’s Compliance Actions on Hold”

  • Bioethics Forum Essay

    Public Citizen: The SUPPORT Study was Even Worse than We Thought

    In his April 18 Bioethics Forum article, John Lantos criticized the findings of the Department of Health and Human Services Office for Human Research Protections that the conduct of the Surfactant,...

    Read “Public Citizen: The SUPPORT Study was Even Worse than We Thought”

  • Bioethics Forum Essay

    The SUPPORT Study and the Standard of Care

    The clinical research community and a number of prominent bioethicists have swiftly come to the defense of investigators conducting the SUPPORT study, in which approximately 1,300 premature infants were randomly...

    Read “The SUPPORT Study and the Standard of Care”

  • Bioethics Forum Essay

    Public Citizen and Misinformed Consent in Neonatal Intensive Care

    Public Citizen, the so-called “citizen’s advocacy group,” continues to criticize the NIH-sponsored clinical trials of oxygen therapy for premature babies.  They followed up their April 10th letter with another, on May 8th. ...

    Read “Public Citizen and Misinformed Consent in Neonatal Intensive Care”

  • Bioethics Forum Essay

    Shame and Guilt in Minnesota

    Over the past month, a petition asking the governor of Minnesota to investigate a research scandal at the University of Minnesota has been steadily gathering momentum.  The scandal in question originated in...

    Read “Shame and Guilt in Minnesota”

  • Bioethics Forum Essay

    OHRP and Public Citizen Are Wrong about Neonatal Research on Oxygen Therapy

    On March 7, 2013, the federal Office of Human Research Protections notified the principal investigator of the Surfactant, Positive Pressure, Oxygenation Randomized Trial (SUPPORT) that “the conduct of this study...

    Read “OHRP and Public Citizen Are Wrong about Neonatal Research on Oxygen Therapy”

  • Bioethics Forum Essay

    After the Media Frenzy, Preventing Another ‘Guatemala’

     I might easily have missed it. I was being a compulsive historian, going to one more archive (having already been to many) to find more material for what would become...

    Read “After the Media Frenzy, Preventing Another ‘Guatemala’”

  • Bioethics Forum Essay

    Kafkaesque and Dickensian: The Human Subjects Protection Maze

    “Mr Mayor,” said K., “you keep calling my case one of the smallest, yet a great many officials have put their minds to it, and while it may have been very...

    Read “Kafkaesque and Dickensian: The Human Subjects Protection Maze”

  • Bioethics Forum Essay

    The Ethical Imperialism of Moral Science

    In December, the Presidential Commission for the Study of Bioethical Issues released a 200-page report, Moral Science: Protecting Participants in Human Subjects in Research. Continuing a decades-old tradition, the report treats...

    Read “The Ethical Imperialism of Moral Science”

  • Bioethics Forum Essay

    Apple and Google Plan to Reinvent Health Care. Should We Worry?

    Editor’s note: This essay responds to an invitation (issued here and here) to submit commentaries on the ethical implications of partnerships between social media companies and biomedical researchers. The invitation...

    Read “Apple and Google Plan to Reinvent Health Care. Should We Worry?”

  • Bioethics Forum Essay

    A FIRST-rate Oversight, and Other Problems with Studies of Medical Residents’ Work Hours

    The rigors of medical and surgical training require long hours dedicated to providing clinical care. While long hours are necessary to obtain the experience to eventually practice independently, performing too...

    Read “A FIRST-rate Oversight, and Other Problems with Studies of Medical Residents’ Work Hours”

  • Bioethics Forum Essay

    Could DTC Genome Testing Exacerbate Research Inequities?

    Editor’s note: This essay responds to an invitation (issued here and here) to submit commentaries on the ethical implications of partnerships between social media companies and biomedical researchers. The invitation...

    Read “Could DTC Genome Testing Exacerbate Research Inequities?”

  • Bioethics Forum Essay

    So You’re a Scholar Who Wants to Make Things Happen

    Because for about the last decade I have been a medical humanist working to change the way physicians treat people born with socially-challenging bodies, I’m frequently asked about doing activism...

    Read “So You’re a Scholar Who Wants to Make Things Happen”

  • Bioethics Forum Essay

    The Vulnerable Researcher and the IRB

    “Why don’t you just go through the IRB process to protect yourself?” one of my colleagues asked me (again) the other day. And I sighed (again). My tendency is to...

    Read “The Vulnerable Researcher and the IRB”

  • Bioethics Forum Essay

    Prenatal Dex: Update and Omnibus Reply

    Our Bioethics Forum essay from a little over a month ago has already spawned three further essays. So we’ve asked the editors to indulge us in this single reply and update....

    Read “Prenatal Dex: Update and Omnibus Reply”

  • Bioethics Forum Essay

    Bad Vibrations

    In “The Rhetoric of Dehumanization: An Analysis of Medical Reports of the Tuskegee Syphilis Project,” Martha Solomon brilliantly demonstrates how the project’s researchers hid their work in plain sight. Specifically,...

    Read “Bad Vibrations”

  • Bioethics Forum Essay

    Preventing Homosexuality (and Uppity Women) in the Womb?

    Two weeks ago, Time magazine reported on our ongoing efforts to protect the rights of pregnant women offered dexamethasone, a risky Class C steroid aimed at female fetuses that may...

    Read “Preventing Homosexuality (and Uppity Women) in the Womb?”

  • Bioethics Forum Essay

    Legal but Unethical: Who Works on That?

    It’s hard to say what is most horrifying in Carl Elliott’s report in the current issue of Mother Jones of a young man who died caught up in a pharma...

    Read “Legal but Unethical: Who Works on That?”

  • Bioethics Forum Essay

    Nationalizing IRBs for Biomedical Research – and for Justice

    I know that when my medical school sends us all an announcement that we’ve broken a record for funded research, I’m supposed to be happy. Wrong week for that. Shortly...

    Read “Nationalizing IRBs for Biomedical Research – and for Justice”

  • Bioethics Forum Essay

    Time for the American Anthropological Association to Apologize

    Last week, the journal Human Nature published via open access an article I wrote following a year of historical research. That article, “Darkness’s Descent on the American Anthropological Association: A...

    Read “Time for the American Anthropological Association to Apologize”

  • Bioethics Forum Essay

    Freedom’s Just Another Word for . . . Restriction?

    What tools does a university administration have at its disposal to shut up critics on its own faculty? The University of Minnesota wants to know. The university’s administration is exploring...

    Read “Freedom’s Just Another Word for . . . Restriction?”

  • Bioethics Forum Essay

    Geron’s Discontinued Stem Cell Trial: What About the Research Participants?

    On November 14, Geron, a pioneer in the field of human embryonic stem cell research, announced that it would discontinue its stem cell programs. This abrupt decision, which shocked the...

    Read “Geron’s Discontinued Stem Cell Trial: What About the Research Participants?”

  • Bioethics Forum Essay

    Fresh Territory for Bioethics: Silicon Valley

    Biomedical researchers are increasingly looking to Silicon Valley for access to human subjects, and Silicon Valley is looking to biomedical researchers for new ventures. These relationships could be a boon...

    Read “Fresh Territory for Bioethics: Silicon Valley”

  • Bioethics Forum Essay

    Response to Call for Essays: Social Media for Genetic Research

    Editor’s note: This essay responds to an invitation (issued here and here) to submit commentaries on the ethical implications of partnerships between social media companies and biomedical researchers. The invitation...

    Read “Response to Call for Essays: Social Media for Genetic Research”

  • Bioethics Forum Essay

    Read the Fine Print Before Sending Your Spit to 23andMe

    Editor’s note: This essay responds to an invitation (issued here and here) to submit commentaries on the ethical implications of partnerships between social media companies and biomedical researchers. The invitation...

    Read “Read the Fine Print Before Sending Your Spit to 23andMe”

  • Bioethics Forum Essay

    Making Big Data Inclusive

    Big Data, which is derived from a multitude of sources including, social media, “wearables,” electronic health records, and health insurances claims, is increasingly being used in health care and it...

    Read “Making Big Data Inclusive”

  • Bioethics Forum Essay

    “Testing in the East”: An Episode in Cold War Bioethics

    In 2013 the influential German magazine Der Spiegel published an expose about clinical trials conducted by Western drug companies in East Germany during the Cold War. The magazine reported that...

    Read ““Testing in the East”: An Episode in Cold War Bioethics”

  • Bioethics Forum Essay

    Shortcomings of the Revised “Helsinki Declaration” on Ethical Use of Health Databases

    Health apps, wearables, and other digital technologies that collect personal health data are profoundly changing the ways that biomedical research is conducted and the role of research participants. These technologies...

    Read “Shortcomings of the Revised “Helsinki Declaration” on Ethical Use of Health Databases”

  • Bioethics Forum Essay

    After the Election Bioethics Faces a Rocky Road

    Academic bioethics has never been popular with Republicans. Libertarians dislike academic bioethics because it seems too elitist and anti-free market.  Religious thinkers worry it is technocratic, soulless and crassly utilitarian....

    Read “After the Election Bioethics Faces a Rocky Road”

  • Bioethics Forum Essay

    The 21st Century Cures Act Sparks Values Debate

    On December 13th, President Obama signed the 21st Century Cures Act, a bipartisan, multidimensional health research and development bill.  The act allocates $4.8 billion to the National Institutes of Health...

    Read “The 21st Century Cures Act Sparks Values Debate”

  • Bioethics Forum Essay

    Insights from Fictional Research Subjects

    Mainstream research ethics rests on an incomplete foundation.  For the most part, human subjects regulations and guidelines reflect the views of professionals and others who have never been subjects themselves. ...

    Read “Insights from Fictional Research Subjects”

  • Bioethics Forum Essay

    Common Rule Revisions: Impact of Public Comment, and What’s Next?

    On January 19, the day the final revisions to the Federal Policy for the Protection of Human Subjects were published in the Federal Register, our essay “Public Engagement, Notice-and-Comment Rulemaking,...

    Read “Common Rule Revisions: Impact of Public Comment, and What’s Next?”

  • Bioethics Forum Essay

    How Can Research with Prisoners Be Done Ethically? Q&A with Charles Lidz

    Clinical research with prisoners is ethically vital and challenging. Studies investigating novel psychological, behavioral, and pharmacological interventions are imperative for the health and experiences of the people they focus on....

    Read “How Can Research with Prisoners Be Done Ethically? Q&A with Charles Lidz”

  • Bioethics Forum Essay

    A Right to Seek Payment for One’s Tissue

    After much anticipation, on April 22, HBO debuted The Immortal Life of Henrietta Lacks, a film based on Rebecca Skloot’s bestselling book, starring Oprah Winfrey. Lacks’s cells provided the foundation...

    Read “A Right to Seek Payment for One’s Tissue”

  • Bioethics Forum Essay

    Is There a Duty to Participate in Biospecimen Research?

    In an essay in the May-June 2017 Hastings Center Report, Holly Fernandez Lynch and Michelle N. Meyer assess the impact of the revised Common Rule on biospecimen research. They believe...

    Read “Is There a Duty to Participate in Biospecimen Research?”

  • Bioethics Forum Essay

    This Doctor Experimented on Slaves: It’s Time to Remove or Redo His Statue

    “There is a difference between remembrance of history and reverence of it,” Mayor Mitch Landrieu declared to explain the removal of four Confederate monuments in New Orleans in May. The...

    Read “This Doctor Experimented on Slaves: It’s Time to Remove or Redo His Statue”

  • Bioethics Forum Essay

    International Sharing of Biological Specimens and Health Data: A Gap in the Consent Process?

    The Precision Medicine Initiative plans to collect data and biological samples from one million or more individuals in the United States and engage in internationally collaborative research. That means that...

    Read “International Sharing of Biological Specimens and Health Data: A Gap in the Consent Process?”

  • Hastings Center News

    Breakthrough Cancer Treatment: Hastings Scholars Discuss Hope and Challenges in Health Affairs

    The first gene therapy for cancer, approved by the Food Drug Administration in August, will transform the treatment of a particular kind of cancer in children and young adults.  It’s...

    Read “Breakthrough Cancer Treatment: Hastings Scholars Discuss Hope and Challenges in Health Affairs”

  • Bioethics Forum Essay

    A Call for Medical Students to Learn the Full Story about the “Father of Gynecology”

    Along with the recent public debates over  Confederate memorials, there have been calls to remove or modify the statue of Dr. J. Marion Sims, called the father of gynecology in...

    Read “A Call for Medical Students to Learn the Full Story about the “Father of Gynecology””

  • Bioethics Forum Essay

    When Are Organ Recipients Human Research Subjects?

    Do the recipients of organ transplants have a right to know if the organs they are about to receive were part of a research study? If so, are the recipients...

    Read “When Are Organ Recipients Human Research Subjects?”

  • Hastings Center News

    How Much Control Should You Have Over Your Biological Data?

    When you donate a sample of blood or saliva for research purposes, is it your property? What about the genetic and other data it contains? Should you be allowed to...

    Read “How Much Control Should You Have Over Your Biological Data?”

  • Bioethics Forum Essay

    Ethical Supervision?

    As I read a recently published report of an interesting and important placebo-controlled trial of arthroscopic shoulder surgery, one sentence in particular caught my eye: “The study was designed under...

    Read “Ethical Supervision?”

  • Bioethics Forum Essay

    A New Mind-Body Problem

    Not since Rene Descartes gazed from his garret window in early 17th-century Paris and wondered whether those were men or hats and coats covering “automatic machines” he saw roaming the...

    Read “A New Mind-Body Problem”

  • Bioethics Forum Essay

    The Need for Open and High Quality Preclinical Science

    An investigative report The BMJ published recently about a failed tuberculosis vaccine trial conducted with infants in South Africa underscores several issues in translational science that are gaining increased attention:...

    Read “The Need for Open and High Quality Preclinical Science”

  • Bioethics Forum Essay

    Palliative Care vs. Cancer Research

    The death of former first lady Barbara Bush at age 92 was noteworthy in many ways. She was by all accounts smart, sharp and funny, and a fine, helpful wife...

    Read “Palliative Care vs. Cancer Research”

  • Bioethics Forum Essay

    Navigating Ethics Review of Human Infection Trials With Zika

    Human infection challenge studies, which deliberately expose healthy volunteers to disease-causing infectious agents under carefully controlled conditions, offer a valuable method of biomedical research aimed at efficient initial efficacy testing...

    Read “Navigating Ethics Review of Human Infection Trials With Zika”

  • Bioethics Forum Essay

    Social Media, Privacy, and Research: A Muddled Landscape

    The advent of social media technology has opened many new avenues of research in population health, demographics, psychology, and the social sciences. It is crucial to consider whether researchers conducting...

    Read “Social Media, Privacy, and Research: A Muddled Landscape”

  • Hastings Center News

    Debating Modern Medical Technologies: The Politics of Safety, Effectiveness, and Patient Access

    Does a new medicine or diagnostic test work? Is it safe? Should the government approve it and insurers pay for it? The answers are not as straightforward as they may...

    Read “Debating Modern Medical Technologies: The Politics of Safety, Effectiveness, and Patient Access”

  • Hastings Center News

    Announcing Ethics & Human Research

    The Hastings Center is announcing an exciting new direction for its journal on research ethics. Beginning with the January-February 2019 issue, the Center will launch Ethics & Human Research (E&HR),...

    Read “Announcing Ethics & Human Research”

  • Bioethics Forum Essay

    Should We Edit the Human Germline? Is Consensus Possible or Even Desirable?

    I started writing this on my way back to New York from the Second International Summit on Human Genome Editing, held in Hong Kong November 27 to 29, where the...

    Read “Should We Edit the Human Germline? Is Consensus Possible or Even Desirable?”

  • Bioethics Forum Essay

    CRISPR in China: Why Did the Parents Give Consent?

    The global scientific community has been unanimous in condemning Chinese scientist He Jiankui, who announced last week that he used the gene-editing technology called CRISPR to make permanent, heritable changes...

    Read “CRISPR in China: Why Did the Parents Give Consent?”

  • Bioethics Forum Essay

    He Jiankui’s Genetic Misadventure, Part 2: How Different Are Chinese and Western Bioethics?

    When the world’s first research on editing the genes of human embryos by Chinese scientists  was published in an international journal in 2015, a report in the New York Times...

    Read “He Jiankui’s Genetic Misadventure, Part 2: How Different Are Chinese and Western Bioethics?”

  • Bioethics Forum Essay

    He Jiankui’s Genetic Misadventure, Part 3: What Are the Major Ethical Issues?

    In their single-minded venture of “producing” (shengchan, in their own word) the world’s first gene-edited babies, He Jiankui and his associates have posed numerous and daunting ethical challenges to China...

    Read “He Jiankui’s Genetic Misadventure, Part 3: What Are the Major Ethical Issues?”

  • Bioethics Forum Essay

    Chinese Bioethicists Respond to the Case of He Jiankui

    A preliminary investigation by Guangdong Province in China of He Jiankui, the scientist who created the world’s first gene-edited babies, found that “He had intentionally dodged supervision, raised funds and...

    Read “Chinese Bioethicists Respond to the Case of He Jiankui”

  • Hastings Center News

    Watch the Livestream: Genomics Enters the Clinic

    What do patients and DTC genetic test consumers need to know about the clinical applications of genetics? That question was the focus of a recent public event at the New York Academy of Sciences, cosponsosred by The Hastings Center. Read a recap of the highlights and watch the livestream.

    Read “Watch the Livestream: Genomics Enters the Clinic”

  • Bioethics Forum Essay

    Hannah Arendt in St. Peter’s Square

    Neither one of us expected to be talking about Hannah Arendt at the Vatican. We had been invited to give talks at the Pontifical Academy of Sciences on the scientific and ethical challenges posed by personalized medicine. Walking across the cobblestones of St. Peter’s Square we began to discuss how society regulates biomedical research. Are institutional review boards capable of dealing with innovations like personalized medicine? Are they too bound by regulations? Can they ask larger questions of meaning when simply following the rules won't suffice? And most worrisome, has their bureaucratic function caused them to mistake regulatory compliance for ethical reflection?

    Read “Hannah Arendt in St. Peter’s Square”

  • Hastings Center News

    New Project Seeks to Build Diverse Participation in Precision Medicine Research

    The Hastings Center is co-leading a new project to examine recruitment and retention of participants the National Institutes of Health’s All of Us Research Program, an unprecedented initiative to collect genetic and other health-related data from at least one million people living in the United States. This project will focus on a research site that is a health center that serves primarily Latino and African American patients -- groups historically underrepresented in research – to identify strategies to build engagement.

    Read “New Project Seeks to Build Diverse Participation in Precision Medicine Research”

  • Hastings Center News

    Five Things Bioethicists See in Our Future

    Read “Five Things Bioethicists See in Our Future”

  • Bioethics Forum Essay

    Transcending Borders in the Ethical Oversight of Human Genome Editing

    The bioethics and legal communities must come together to find ways to move with the same ease of the scientific research community--to transcend the geopolitical borders and jurisdictional concerns that make international regulation so difficult.

    Read “Transcending Borders in the Ethical Oversight of Human Genome Editing”

  • Bioethics Forum Essay

    Clinical Trials vs. Right to Try: Ethical Use of Chloroquine for Covid-19

    Double-blind randomized clinical trials are the gold standard for answering the scientific question of whether a drug produces any effect, positive or negative, in Covid-19 patients. But is rational for a patient to choose to try a drug such as chloroquine for Covid-19 outside of a trial? Some patients may correctly hold that they have little to lose.

    Read “Clinical Trials vs. Right to Try: Ethical Use of Chloroquine for Covid-19”

  • Bioethics Forum Essay

    Ethical Responsibility in Publishing Research Results on Covid-19 Treatments

    There is little doubt about the urgent need for Covid-19 treatment. But premature publication of definitive recommendations based on inappropriate conclusions grounded in scant, hastily-acquired data serve only at best to confuse and at worst mislead at a time when tensions are high and need for help is great.

    Read “Ethical Responsibility in Publishing Research Results on Covid-19 Treatments”

  • Bioethics Forum Essay

    Volunteering for a Covid Vaccine Trial: Fulfilling Hindu Obligations or Fostering Pharmaceutical Company Profits?

    Volunteering for a Covid-19 vaccine trial satisfied my altruistic goals and harmonizes with my Hindu beliefs. But I am troubled that a drug company is going to profit from my altruism and my religious obligations.

    Read “Volunteering for a Covid Vaccine Trial: Fulfilling Hindu Obligations or Fostering Pharmaceutical Company Profits?”

  • Bioethics Forum Essay

    Ethics of Placebo Controls in Coronavirus Vaccine Trials

    Multiple candidate vaccines for coronavirus are being evaluated scientifically in a process of unprecedented speed, and thousands of individuals around the world have volunteered to participate in placebo-controlled phase III field trials. If, or when, one of these candidate vaccines is proved to be safe and effective and receives an emergency use authorization by the Food and Drug Administration, will it continue to be ethical to enroll participants in other coronavirus trials that randomize half of them to a placebo?

    Read “Ethics of Placebo Controls in Coronavirus Vaccine Trials”

  • Bioethics Forum Essay

    Should We Enroll Our Child in a Covid-19 Vaccine Trial?

    My partner and I are thinking a lot about this question. Moderna and Pfizer trials are running in our community–at the children’s hospital where I work as a clinical ethicist....

    Read “Should We Enroll Our Child in a Covid-19 Vaccine Trial?”

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    Should the FDA Have Approved the New Alzheimer’s Drug?

    Should Patients Take It? Monday, July 12, 2021 The Food and Drug Administration’s accelerated approval of a new Alzheimer’s drug has created a firestorm of praise and outrage. Dissenters include...

    Read “Should the FDA Have Approved the New Alzheimer’s Drug?”

  • Hastings Center News

    TRANSCRIPT – Breakthrough or Breakdown: Should the FDA Have Approved the New Alzheimer’s Drug?

    [Transcript created by voice recognition] Danielle Pacia, The Hastings Center Hello and welcome to Breakthrough or Breakdown. Should the FDA have approved the new Alzheimer’s drug, a Hastings Center conversation?...

    Read “TRANSCRIPT – Breakthrough or Breakdown: Should the FDA Have Approved the New Alzheimer’s Drug?”

  • Bioethics Forum Essay

    Fear of Doing Too Much Too Soon or Too Little Too Late: Research on Covid-19

    The Covid-19 pandemic has significantly affected the practice of clinical research. Researchers and IRBs have felt an urgency to respond more quickly than usual, aware that lives are at stake.

    Read “Fear of Doing Too Much Too Soon or Too Little Too Late: Research on Covid-19”

  • Page

    Justice in Health: Equipping Bioethics to Improve Policy and Practice

    Project Director: Josephine Johnston Funder: The Greenwall Foundation This project was a collaboration between an independent antiracism task force of bioethicists from across the United States and The Hastings Center, as part...

    Read “Justice in Health: Equipping Bioethics to Improve Policy and Practice”

  • Hastings Center News

    Eliminating Racial Health Inequities: An IRB’s Antiracist Intervention

    The use of racial categories in biomedical research often misattributes the cause of health inequities to genetic and inherent biological differences rather than to racism. Improving research practices around race...

    Read “Eliminating Racial Health Inequities: An IRB’s Antiracist Intervention”

  • Bioethics Forum Essay

    Newly Released Documents from Untreated Syphilis Study: Ethical, Just, and Respectful Use of Archival Materials

    To mark the 50th anniversary of the end of the United States Public Health Service’s Syphilis Study, the National Library of Medicine recently digitized and released reams of historical documents on the “origin and development of the Tuskegee syphilis study.” The release of these documents is a poignant occasion to consider what qualifies as ethical, just, and respectful use of archival materials.

    Read “Newly Released Documents from Untreated Syphilis Study: Ethical, Just, and Respectful Use of Archival Materials”

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