Ethics & Human Research
- Ethics & Human Research
SARS-CoV-2 Human Challenge Trials: Rethinking the Recruitment of Healthy Young Adults First
Early View
Read the PostEthics & Human ResearchIn the midst of the ongoing Covid-19 pandemic, researchers across the globe are working to develop an effective vaccine. To expedite this process even further, human challenge trials have been proposed by the World Health Organization (WHO) as an alternative to conventional approaches. In such trial...Read the Post - Ethics & Human Research
Human Infection Challenge Experiments: Then and Now
Early View
Read the PostEthics & Human ResearchIn the midst of the Covid-19 pandemic, ethicists, researchers, and journalists have recommended studies that deliberately infect healthy volunteers with the coronavirus as a scientific means of expediting vaccine development. In this essay, we trace the history of infection challenge experiments and...Read the Post - Ethics & Human Research
Ethical Inclusion of Health Care Workers in Covid-19 Research
March-April 2021
Read the PostEthics & Human ResearchAbstract: Employees are often considered a vulnerable research population due to concerns about consent and confidentiality, but there is insufficient guidance regarding their ethical inclusion in research. In the context of Covid-19, frontline health care workers comprise a particularly relevant re...Read the Post - Ethics & Human Research
The Ethics of Repurposing Previously Collected Research Biospecimens in an Infectious Disease Pandemic
March-April 2021
Read the PostEthics & Human ResearchIn the early days of a pandemic, repurposing biospecimens from established research projects could prove to be extraordinarily useful in achieving substantial and timely public health benefits. Nonetheless, there are potential ethical and regulatory uncertainties that may impede access to those valu...Read the Post - Ethics & Human Research
Governing AI‐Driven Health Research: Are IRBs Up to the Task?
March-April 2021
Read the PostEthics & Human ResearchMany are calling for concrete mechanisms of oversight for health research involving artificial intelligence (AI). In response, institutional review boards (IRBs) are being turned to as a familiar model of governance. Here, we examine the IRB model as a form of ethics oversight for health research th...Read the Post - Ethics & Human Research
Commentary: Balancing External Validity and Concern for Psychosocial Harms in Translational Genetic Research
March-April 2021
Read the PostEthics & Human ResearchIn this commentary, we explore a challenge to translational genetic research: how to balance protecting research participants with ensuring the external validity of research so that research results are implemented in ways that protect future patients. Using our experience with a recently awarded Na...Read the Post - Ethics & Human Research
Case Study: Unblinding in Randomized Controlled Trials: A Research Ethics Case
March-April 2021
Read the PostEthics & Human ResearchA pregnant woman was enrolled in a double‐blind randomized controlled trial (RCT) in which participants were randomized to a placebo or a drug being tested to prevent a hypertensive complication. After completing the trial, the research participant insisted on being told which drug she received to...Read the Post - Ethics & Human Research
Should the Regulation of Research Misconduct Be Integrated with the Ethics Framework Promulgated in The Belmont Report?
January-February 2021
Read the PostEthics & Human ResearchThe federal research misconduct regulations finalized in 2005 did not incorporate important principles regarding human subjects protections articulated in The Belmont Report, yet research misconduct can involve harms to research subjects and to subsequent patients whose treatments are based on false...Read the Post
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Ethics & Human Research (formerly IRB: Ethics & Human Research) aims to foster critical analysis of issues in science and health care that have implications for human biomedical and behavioral research, including developments that bring new challenges to existing ethical, regulatory, and policy frameworks governing research with humans in the United States and elsewhere. Six issues are published each year, containing an assortment of commentaries, case studies, peer-reviewed scholarly articles, and book reviews.
To access supporting information for articles in E&HR, such as tables, figures, and appendices that do not appear in the journal itself, see this page.
For prior issues of IRB: Ethics & Human Research, please visit Jstor.org.
Authors include experts in research ethics who come from a wide range of academic disciplines and professions, researchers who conduct biomedical and behavioral research, and policy-makers. We welcome submissions from new authors. E&HR’s readership includes ethics committee members, institutional leaders, researchers, and scholars from many academic disciplines.
Our submissions guidelines can be found here.
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| Karen J. Maschke, editor
Laura Haupt, managing editor Julie Chibbaro, staff editor Nora Porter, art director |
Editorial Board
Laura Beskow, PhD, MPH Vanderbilt University Barbara Bierer, MD Harvard University Alex Capron, LLB University of Southern California Stephanie Solomon Cargill, PhD St. Louis University Rebecca S. Dresser, JD, MS Washington University in St. Louis Carl Elliott, MD, PhD University of Minnesota Holly Fernandez Lynch, JD, MBE University of Pennsylvania Joseph J. Fins, MD Weill Cornell Medical College Paul Ford, PhD Cleveland Clinic Cristine Grady, MSN, PhD National Institutes of Health Clinical Center Steven Joffe, MD, MPH University of Pennsylvania Jonathan Kimmelman, PhD McGill University Nancy M. P. King, JD Wake Forest University Susan Lederer, PhD University of Wisconsin–Madison Alex John London, PhD Carnegie Mellon University Suzanne Rivera, PhD, MSW Case Western Reserve University Mark A. Rothstein, JD University of Louisville Laura Stark, PhD Vanderbilt University Jeremy Sugarman, MD, MPH, MA Johns Hopkins University Benjamin S. Wilfond, MD Seattle Children’s Research Institute |
ISSN 2578-2355 print; ISSN 2578-2363 online
Publisher: Wiley