The need for socially responsible communication about genomics research is greater than ever. New research into genomic influences on traits such as intelligence, educational attainment, household income, and sexual behavior is drawing media attention and public scrutiny. These social and behavioral...

Framing the Issue DNA has been a powerful crime-solving tool for decades, but law enforcement’s ability to harness it for investigative purposes has grown immensely in recent years. This is due primarily to the massive amount of genetic data now housed in government-run, public, and private databas...

Framing the Issue The completion of the Human Genome Project in 2003 ushered in technological advancements that have made genetic information more accessible to researchers and the public than ever before. While scientists have traditionally studied human genetics using twin, family, and adoptio...

In his recent piece, “The genes we’re dealt,” Erik Parens puts his finger on cause for concern with what he calls social genomics: while progressives can use insights from this new field to justify combating inequality, conservatives can use them to justify the existence of that same inequality. This pessimistic conclusion—which Parens argues convincingly for—follows from a focus on insights at the societal level, that of a whole population. But there are grounds for optimism by focusing instead on potential insights from social genomics derived from local-level comparisons between different environments. Such insights could point to interventions that progressives and conservatives might just be able to agree on.

Over the past decade, the new field of social genomics has investigated how genomic differences among people are linked to differences in their behaviors and social outcomes, including educational attainment and socioeconomic success. But the findings can be interpreted differently by progressives a...

Hastings Center postdoctoral researcher Lucas J. Matthews is undertaking the first-ever study to examine the potential harms of telling students about their genetic propensity for educational attainment.

The bioethics and legal communities must come together to find ways to move with the same ease of the scientific research community--to transcend the geopolitical borders and jurisdictional concerns that make international regulation so difficult.

The Compassionate Use Advisory Committee, headed by Hastings Center Fellow Arthur Caplan, of NYU Langone, received the Reagan-Udall Foundation for the Food and Drug Administration’s Innovation Award. The committee was recognized for transforming how expanded access requests, also known as compassionate use requests, are granted by drug developers.

Last week, the Trump Administration proposed a new rule that would “require DNA-sample collection from individuals who are arrested, facing charges, or convicted, and from non-United States persons who are detained under the authority of the United States.” Collecting DNA of people detained under the Department of Homeland Security is not permitted under U.S. law. The proposed rule aims to change that.

Scientists have high hopes for using “polygenic risk scores” to better understand social and behavioral characteristics such as intelligence and obesity. But much behavioral genetics research has an ugly history and contemporary research risks exacerbating health inequities. A new Hastings Cente...

Lucas J. Matthews has been named a postdoctoral researcher at The Hastings Center and the Columbia Center for Research on Ethical, Legal & Social Implications of Psychiatric, Neurologic & Behavioral Genetics. In this two-year position, he will take on conceptual, methodological, and ethical ...

New book edited by Hastings Center scholars explores fundamental questions about the nature and well-being of human beings at a time when a revolutionary new biotechnology could permanently change the human species.

The Hastings Center is a collaborator on a major new federally funded center – the Center for ELSI Resources and Analysis — that will fill a void in genetics research by collecting and sharing information about its ethical, legal, and social (ELSI) implications. This resource hub, the first ...

For the last quarter century, researchers have been asking whether genetic information might have negative psychosocial effects. Anxiety, depression, disrupted relationships, and heightened stigmatization have all been posited as possible outcomes—but not consistently found. What accounts for the ...

What do patients and DTC genetic test consumers need to know about the clinical applications of genetics? That question was the focus of a recent public event at the New York Academy of Sciences, cosponsosred by The Hastings Center. Read a recap of the highlights and watch the livestream.

The protections of GINA play a key role in the decision of many of my healthy patients to decide to undergo genetic testing. My criticism is that GINA is unfair to people who might suffer discrimination in health. insurance for non-genetic reasons.

Genetics is finally being integrated into the clinic: cancer patients are having their cancer’s genome sequenced, fertility patients are having their embryos tested, and parents are being offered sequencing of their newborn babies.

Advances in preimplantation genetic diagnosis, genetic testing, and genome editing have renewed discussion about the ethics of “designer babies,” or children selected or engineered to have certain preferred traits, like superior intelligence or tall stature. But the same techniques used to create...

Three journalists received The Hastings Center Awards for Excellence in Journalism on Ethics and Reprogenetics. The awards were presented at an event in New York City on December 6 that celebrated the role of journalists in helping the public understand the science of heredity and the power of geneti...

Several DNA tests claim to predict how well particular psychiatric medications are likely to work for individual patients with depression, bipolar disorder, and schizophrenia. And 23andMe just received approval to market the first direct-to-consumer pharmacogenomics report, which detects 33 variants ...

With the popularity of direct-to-consumer genetic testing, genomic knowledge is assuming a growing role in shaping human life. On the one hand, this knowledge is a gift, offering insights into the genetic drivers of disease and the geographical paths of our ancestors. On the other hand, it is a weigh...

In late April, a suspect thought to be the Golden State Killer, a man who had eluded police for decades after committing a string of murders and rapes in Northern California and Orange County between 1976 and 1986, was identified on the basis of DNA evidence. Although we celebrate the dogged pursuit ...

The process is fairly simple. You select one of the companies that offer direct-to-consumer genetic tests; pay online; receive a neatly packed kit that contains a tube designed to collect your spit; return the package using prepaid postage; and wait for the results that will unravel the mysteries of ...

Hastings Center president Mildred Z. Solomon and director of research Josephine Johnston were featured speakers at the premiere screening of The Code, a series of three documentaries on the origins of genetic medicine and what its successes and failures mean for the future. The series was produced by...

For the last quarter century, researchers have been asking whether genetic test results might have negative psychosocial effects. Anxiety, depression, disrupted relationships, and heightened stigmatization have all been posited as possible outcomes—but not consistently found. What accounts for the ...

Before noninvasive prenatal screening becomes a routine part of gestational care, society needs to have difficult conversations about the ethical implications and establish a paradigm for truly informed consent in reproductive decision-making. These are admirable goals, set out in an article by Vardi...

Climate change, nuclear proliferation, and the advancement of gene editing and other transformative biotechnologies pose enormous global challenges. How can we promote responsible science, good governance, and opportunities for public engagement at time when anti-intellectualism on the rise and socie...

Is there a parental obligation to create “better” babies? Now that scientists can genetically edit plants and animals for agricultural and other purposes, what can we learn from the longstanding international debate over GMOs?

The Oxford philosopher Julian Savulescu, among others, has argued that prospective parents engaging in embryo selection using preimplantation genetic diagnosis not only may seek to have genetically enhanced children but are morally obligated do so. (See, for example, his essay “Procreative Benefice...

Noninvasive fetal genetic sequencing done early in pregnancy is poised to become a routine part of prenatal care. While it could offer patients substantial benefits, there is a risk that it will be integrated into care “without the robust, evidence-based informed consent process necessary for respe...

This was one of the many big questions explored at Genomics and Society, a major conference last week on the ethical, legal, and social implications of genomic research.

There is a broad and deep moral conviction that health care should be distributed according to genuine need and not left to the cold mercy of pure market forces or the logic of actuarial fairness. Unfortunately, the proposed American Health Care Act (AHCA), passed last week in the House of Representatives, and other legislation threaten to undermine that moral commitment.

Braingenethics Update, a free monthly newsletter, aggregates recent scientific literature, commentary, and news on questions raised by findings on the genetics of complex human behaviors. It is produced by the Columbia University College of Physicians and Surgeons and The Hastings Center as part of a...

What lessons does Frankenstein hold for us today, when powerful new technologies such as gene editing and artificial intelligence are bringing us closer than ever to playing God? That question was the focus of  “Spawn of Frankenstein,” a public event that featured Josephine Johnston, dir...

Some researchers are at work generating images of people’s faces by relying on DNA samples alone, in a process known as DNA phenotyping.The process involves linking genetic traits and their typical manifestations in traits such as eye color, hair color, and features associated with ancestry. The r...

In the early 2000s, Avshalom Caspi, Terrie Moffitt, and their colleagues published two papers (here and here), which suggested that we could finally begin to tell rather simple but evidence-based stories about how genetic and environmental variables interact to influence the emergence of complex ph...

 

Ethicists and others have been concerned that the disclosure of genetic information to patients might have negative consequences. The suspicion has been that negative effects, say, becoming depressed, are particularly likely when people are being informed about predispositions to diseases that are no...