How should we work to address climate change and other planetary threats to human health and survival? Our society is built on a global economy that is extractive and destructive, not only to the planet but to people and societies. What is needed to shift to an economic system that does not externalize harm, given the implications for human and planetary health? This year, Gary Cohen, president of Health Care Without Harm, an organization focused on the intersection of health care, climate change, and health equity, will discuss these questions and more with Mildred Z. Solomon, president of the Hastings Center, at the Daniel Callahan Annual Lecture on April 19 at noon Eastern Time.