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• HASTINGS CENTER NEWS

  And what does “humanize” even mean? Those are among the questions being explored in a new Hastings Center project, funded by the National Institutes of Health, on the ethical oversight of research with human-animal chimeras, laboratory animals that contain human cells. With recent scientific advances, scientists are better equipped than ever to insert human cells… Read more

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  HASTINGS CENTER NEWS

  

  New Project: Could Human Cells “Humanize” Research Animals?

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• HASTINGS CENTER NEWS

  Hastings Center research scholar Carolyn P. Neuhaus participated in a panel discussion on Martha’s Vineyard on July 12 to discuss a proposal to release genetically modified mice to curb the spread of Lyme disease and other tick-borne illnesses. A Netflix film crew recorded the event, which featured Kevin Esvelt, an evolutionary biologist at MIT. Michael… Read more

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  Should Gene-Edited Mice Be Released to Control Lyme Disease?

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• BIOETHICS FORUM ESSAY

  In early 2016, Nature published a letter from a group of Chinese researchers reporting that they had created rhesus macaques with “autism-like” behaviors. The macaque was bred with a mutation in the MeCP2 gene. Overexpression of MeCP2 is found in MeCP2 duplication syndrome, a disorder that shares many of its core symptoms with autism spectrum… Read more

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  Is it Ethical for Scientists to Create Nonhuman Primates with Brain Disorders?

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• BIOETHICS FORUM ESSAY

  Scientists acknowledge biological, behavioral, and psychological similarities between human and nonhuman primates; hence their use as proxies in biomedical research. At the same time, primates are denied many ethical considerations and basic protections afforded to humans participating in research. The National Institutes of Health recently had an excellent opportunity to consider the moral arguments for… Read more

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  Missing from NIH Primate Research Ethics Review: the Ethics

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• BIOETHICS FORUM ESSAY

  “If you look through the red-tinted glass, you will see the radioactive pig,” said the director of animal laboratories at my university–let’s call her Susan–near the start of my tour of the facility. There on a concrete floor, within a steel cage, was a large solitary sow, lying on her side, legs pointed left. I… Read more

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  On a Radioactive Pig and Pope Francis

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• BIOETHICS FORUM ESSAY

  Decades of experiments have shown that rats are smart individuals that feel pain and pleasure, care about one another, can read others’ emotions, and will help unfamiliar rats even at a cost to themselves. It’s time to apply what we’ve learned from these animals and stop conducting experiments on them in laboratories. Recently, there was substantial media… Read more

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  Rats Have Empathy, But What About the Scientists Who Experiment on Them?

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• BIOETHICS FORUM ESSAY

  The institution of animal experimentation is a house of cards, and a stiff wind is blowing at last. At a meeting last month about federal funding for science, former National Institutes of Health director  Elias Zerhouni admitted that experimenting on animals has been a boondoggle. “We have moved away from studying human disease in humans,” he said.… Read more

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  As Chimp Research is Phased Out, Will Other Animal Research Decline?

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• BIOETHICS FORUM ESSAY

  Two announcements today have changed the conversation about the use of chimpanzees in research. The first announcement came from an Institute of Medicine committee and its much-anticipated report on the necessity of chimpanzees in biomedical and behavioral research. The report concluded that most of this research is unnecessary. Though it did not call for a ban on the research,… Read more

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  Good News for Chimpanzees in U.S. Labs

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• BIOETHICS FORUM ESSAY

  I am opposed to animal experimentation. However, I do not for a moment deny that reasonable and well-meaning people can disagree about this issue. I am all for vigorous debate. But in order to be intelligent, the debate must employ terminology whose meaning is understood by all parties, including the audience or reader. In the… Read more

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  What is Humane? A Plea for Plain Language in the Debates on Animal Experimentation

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• BIOETHICS FORUM ESSAY

  When antivivisectionists protest the use of animals in biomedical research, they are commonly met with retorts like this: “Our faculty members employ animals only when there are no alternative models for advancing their research; our laboratories comply with or exceed all federal regulations and independent accreditation standards. As we continue to advance modern medicine, and… Read more

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  Why Animal Experimenters Should Be Vegetarians

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