jsc2024e006094 (1/18/2024) --- Cross-section of a two-month old cerebral organoid observed under a fluorescence microscope. The colours obtained by immunofluorescence labeling highlight certain elements of the organoid’s structure. In blue the cell nuclei, in green, a sub-population of immature neurons, and in red, neurogenic zones with a high concentration of stem cells, in the shape of rosettes, where new neurons are forming. Credit: Institut Pasteur-SupBiotech.

Ethics & Human Research

Translational Bioethical Decision-Making: Human Brain Organoids as a Case Study

ABSTRACT In an earlier essay, I advocated that translational bioethics uses the public’s values, determined through social science, in its analysis of translational science technologies. It may be unclear what those values might be, and whether such a translational ethics would necessarily conclude that cutting edge technologies should not be developed. In this essay, I show the public’s values relevant to human brain organoids and argue that a translational bioethics analysis using these values would support continued organoid research.

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