DNA genes of human chromosome as symbol for genetic research and biotechnology

Ethics & Human Research

Commentary: Balancing External Validity and Concern for Psychosocial Harms in Translational Genetic Research

In this commentary, we explore a challenge to translational genetic research: how to balance protecting research participants with ensuring the external validity of research so that research results are implemented in ways that protect future patients. Using our experience with a recently awarded National Institutes of Health (NIH) grant, we highlight the importance of external validity in ensuring that the results of translational studies are responsibly and ethically implemented in clinical practice and do not compromise the welfare of future patients whose care the study results are meant to inform.

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